Canadian Association of Wound Care Home Search Disclaimer Français
   

Back to Research

     
   

ELECTRICAL STIMULATION

Gardner SE, Frantz RA,, Schmidt FL. Effect of electrical stimulation on chronic wound healing: a meta analysis. Wound Repair Regen 7; 495-503, 1999.

Alon G, Azaria M, Stein H. Diabetic ulcer healing using high voltage TENS. Phys Ther 1986; 66:775.

Assimacopoulos, D. Low intensity negative electric current in the treatment of ulcers of the leg due to chronic venous insufficiency. Am J Surg 1968;115:683-687.

Baker LL, Rubayi S, Villar F, Demuth SK. Effect of electrical stimulation waveform on healing of ulcers in human beings with spinal cord injury. Wound Rep Reg 1996; 4:21-28.

Baker LL, Chambers R, DeMuth SK, Villar F. Effects of electrical stimulation on wound healing in patients with diabetic ulcers. Diabetes Care 1997; 20:405-411.

Barron JJ, Jacobson WE, and Tidd G. Treatment of decubitus ulcers. Minnesota Medicine 1985;103-106.

Carley PJ and Wainapel SF. Electrotherapy for accleration of wound healing: low intensity direct current. Arch Phys Med Rehabil 1985;66:443-446.

Feedar JA, Kloth LC, and Gentzkow GD. 1991. Chronic dermal ulcer healing enhanced with monophasic pulsed electrical stimulation. Phys Ther 71:639-649.

Fitzgerald GK, and Newsome D. Treatment of a large infected thoracic spine wound using high voltage pulsed monophasic current. Phys Ther 1993;73:355-360.

Gault WR, and Gatens PF. Use of low intensity direct current in management of ischemic skin ulcers. Phys Ther 1976; 56:265-269.

Gentzkow GD, Alon G, Taler GA, Eltorai IM, and Montroy RE. Healing of refractory stage III and IV pressure ulcers by a new electrical stimulation device. Wounds 1993;5:160-172.

Griffin J W, Tooms RE, Mendius RA, Clifft JK, Vander Zwaag R, and El-Zeky F. Efficacy of high voltage pulsed current for healing of pressure ulcers in patients with spinal cord injury. Phys Ther 1991;71:433-444.

Houghton, PE, Kincaid CB, Lovell M, Campbell KE, Woodbury MG, Keast DK, Harris KA. Effect of electrical stimulation on chronic leg wounds due to vascular insufficiency. Physical Therapy (in press), 2002.

Jacques PF, Brogan MS, and Kalinowski D. High-voltage electrical treatment of refractory dermal ulcers. Physician Assistant 1997;84-91.

Kaada B. Promoted healing of chronic ulceration by transcutaneous nerve stimulation (TNS). VASA 1983;12:262-269.

Katelaris PM, Fletcher JP, Little JM, McEntyre RJ, and Jeffcoate KW. Electrical stimulation in the treatment of chronic venous ulceration. Aust N Z J Surg 1987;57:605-607.

Kloth LC, and Feedar JA. Acceleration of wound healing with high voltage, monophasic, pulsed current. Phys Ther 1988;68:503-508.

Lundeberg TCM, Eriksson SV, Malm M. Electrical nerve stimulation improves healing of diabetic ulcers. Ann Plas Surg 1992;29:328-330.

Mulder GD. Treatment of open-skin wounds with electric stimulation. Arch Phys Med Rehab 1991;72:375-377.

Rischbieth H, Jelbart M, Marshall R. Neuromuscular electrical stimulation keeps a tetraplegic subject in his chair: A case study. Spinal Cord 1998; 36:443-445.

Thurman BF, and Christian EL. Response of a serious circulatory lesion to electrical stimulation. Phys Ther 1971;3:1107-1110.

Wolcott LE, Wheeler PC, Hardwicke HM & Rowley BA. Accelerated healing of skin ulcers by electrotherapy: Preliminary clinical results. South Med J 1969;62:795-801.

Wood, J. M., P. E. Evans, K. U. Schallreuter, W. E. Jacobson, R. Swift, J. Newman, C. White, and M. Jacobson. 1993. A multicenter study on the use of pulsed low-intensity direct current for healing chronic stage II and stage III decubitus ulcers. Arch Dermatol 129:999-1009.

THERAPEUTIC ULTRASOUND

Johannsen F, Nyholm A, Karlsmark T. Ultrasound therapy in chronic leg ulceration: a meta-analysis. Wound Repair Regen 1998; 6:121-126.

Brueton RN, Campbell B. The use of geliperm as a sterile coupling agent for therapeutic ultrasound. Physiotherapy 1987; 73:653-654.

Callam MJ, Dale JJ, Harper DR, Ruckley CV. A controlled trial of weekly ultrasound therapy in chronic leg ulceration. The Lancet 1987; 204205

Dyson M, Franks C, Suckling J. Stimulation of healing of varicose ulcers by ultrasound. unknown 1976; 232-236.

Eriksson SV, Lundeberg T, Malm M. A placebo controlled trial of ultrasound therapy in chronic leg ulceration. Scandinavian Journal Of Rehabilitative Medicine 1991; 23:211-213.

Forrest G, Rosen K. Ultrasound: Effectiveness of treatments given under water. Arch Phys Med Rehabil. 70:28-29, 1989.

Lundeberg T, Nordstrom F, Brodda-Jansen G, Eriksson SV, Kjartansson J, Samuelson UE. Pulsed ultrasound does not improve healing of venous ulcers. Scand J Rehab med 1990; 22:195-197.

McDiarmid T, Burns PN, Lewith GT, Machin D. Ultrasound and the treatment of pressure sores. Physiotherapy 1985; 71:

Nussbaum EL, Biemann I, Mustard B. Comparison of ultrasound/ultraviolet-C and laser for treatment of pressure ulcers in patients with spinal cord injury. Physical Therapy 1994; 74:812-825.

Paul BJ, Lafratta CW, Dawson AR, Baab E, Bullock F. Use of ultrasound in the treatment of pressure sores in patients with spinal cord injury. Archives of Physical Medicine and Rehabilitation 1960; 438-440.

Peschen M, Weichenthal M, Schopf E, Vanscheidt W. Low-frequency ultrasound treatment of chronic venous leg ulcers in an outpatient therapy. Acta Derm Venereol (Stockh) 1997; 77:311-314.

Roche C, West J. A Controlled Trial Investigating the Effect of Ultrasound on Venous Ulcers Referred from General Practitioners. Physiotherapy 1984; 70:475-477.

ter Riet G, Kessels AGH, Knipschild P. A randomized clinical trial of ultrasound in the treatment of pressure ulcers. Physical Therapy 1996; 76:1301-1311.

Weichenthal M, Mohr P, Stegmann W, Breitbart EW. Low-frequency ultrasound treatment of chronic venous ulcers. Wound Repair and Regeneration 1997; 5:18-22.

RADIOFREQUENCY/ELECTROMAGNETIC FIELDS

Comorosan S, Vasilco R, Arghiroplo M, et al., Effects of Diapulse therapy on the healing of decubitus sores. Romanian J of Phys (Physiological Sciences) 1993;30:1-2.

Goldin JH, Broadbent NRG, Nancarrow JD, and Marshall T. The effects of Diapulse on the healing of wounds: a double-blind randomised controlled trial in man. Br J Plas Surg 1981;34:267-270.

Ieran M, Zaffuto S, Bagnacani M, Annovi M, Moratti A, and Cadossi R. Effect of low frequency pulsing electromagnetic fields on skin ulcers of venous origin in humans: a double-blind study. J Ortho Res 1990:276-282.

Itoh M, Montermayor JS, Matsumoto E et al. Accelerated wound healing of pressure ulcers by pulsed high peak power electromagnetic energy (Diapulse). Decubitus 1991;4(1):24-34.

McMeeken JM. Magnetic fields: effects on blood flow in human subjects. Physiother Theory Practice 1992;8:3-9.

Mayrovitz H, Larsen P. Effects of pulsed electromagnetic fields on skin microvascular blood perfusion. Wounds 1992;4(5):197-202.

Mayrovitz H, Larsen P. A preliminary study to evaluate the effect of pulsed radio frequency field treatment on lower extremity periulcer skin microcirculation of diabetic patients. Wounds 1995;7(3):90-93.

Santoro D, Ostrander L, Lee BY, Cagir B. (1994) Inductive 27.12 MHz Diathermy in Arterial Peripheral Vascular Disease. 16th International IEEE/EMBS Conference; October 1994; Montreal Quebec.

Salzberg CA, Cooper-Vastola SA, Perez F, Viehbeck MG, and Byrne DW. The effects of non-thermal pulsed electromagnetic energy on wound healing of pressure ulcers in spinal cord-injured patients: a randomized, double-blind study. Ostomy/Wound Manage 1995;41:42-51.

Seaborne D, Quirion-DeGirardi C, Rousseau M, Rivest M, and Lambert J. The treatment of pressure sores using pulsed electromagnetic energy (PEME). Physiother Can 1996;48:131-137.

Stiller MJ, Pak GH, Shupack JL, Thaler S, Kenny C, and Jondreau L. A portable pulsed electromagnetic field (PEMF) device to enhance helaing of recalcitrant venous ulcers: a double-blind, placebo-controlled clinical trial. Br J Dermatol 1992;127:147-154.

LASER

Gam AN, Thorsen H, Lonnberg F. The effect of low-level laser therapy on musculoskeletal pain: a meta analysis. Pain 1993;52:63-66.

Beckerman H, deBie RA, Bouter LM, DeCuyper HJ, Oostendorp RAB. The efficacy of laser therapy for musculoskeletal and skin disorders: a criteria-based meta-analysis of randomized clinical trials. Phys Ther 1992;72(7):483-91.

Crous LC, Malherbe CP. Laser and ultraviolet light irradiation in the treatment of chronic ulcers. Physiother 1988;44(3):73-7.

Gogia PP, Hurt BS, Zirn TT. Wound management with whirlpool and infared cold laser treatment. Phys Ther 1988;68(8):1239-42.

Gogia PP, Marquez RR. Effects of helium neon laser on wound healing. Ostomy/Wound Manage. 1992;38:33-41.Horwitz LR, Burke TJ, Carnegie D. Augmentation of wound healing using monochromatic infrared energy. Adv in Wound Care 1999;12:35-40.

Kleinkort J, and Foley R. Laser: a preliminary report on its use in physical therapy. Clin Manage Phy Ther 1982;2:30-32.

Kahn J. Case reports: open wound management with the HeNe cold laser. JOSPT 1984;6:203-204.

Mester AF, Mester A. Wound Healing Low Level Laser Therapy (LLLT). 1989;7-15.

Malm M, Lundeberg T. Effect of low power gallium arsenide laser on healing of venous ulcers. Scand J Plast Reconstr Hand Surg 1991;25:249-51.

Santoianni P, Monfrecola G, Martellotta D, Ayala F. Inadequate effect of helium-nwon laser on venous leg ulcers. Photodermatol 1984;1:245-9.

Schindl A, Schindl M, Schindl L. Successful treatment of a persistent radiation ulcer by low power laser therapy. J Am Acad Dermatol 1997;37(4):646-9.

Shuttleworth E, & Banfield K. Light Relief. Wound Care 1996; 70-78.

ULTRAVIOLET LIGHT C

Burger A, Jordaan M, Schoombee G. Die Kiemdodende Effek van Ultravioletlig op Geinfekteerde Druksere. Physiotherapy 1985; 41:55-57.

Crous LC, Malherbe CP. Laser and ultraviolet light irradiation in the treatment of chronic ulcers. Physiotherapy 1988; 44:73-77.

Freytes, H., Fernandez B and Flemming W. Ultraviolet light in the treatment of indolent ulcers. South Med J 1965; 58;223.

MacKinnon JL, Cleek PJ. The penetration of ultraviolet light through transparent dressings. Physical Therapy 1983; 204

Nussbaum EL, Biemann I, Mustard B. Comparison of ultrasound/ultraviolet-C and laser for treatment of pressure ulcers in patients with spinal cord injury. Physical Therapy 1994; 74:812-825.

Thai TP, Houghton PE, Keast DH, Woodbury MG, Campbell KE. Effects of ultraviolet light C on the bacterial burden in chronic ulcers. OstomyWound Manage 47(11): 51, 2001.

Wills E, Anderson T, Beattie B, Scott A. A Randomized Placebo-controlled Trial of Ultraviolet Light in the Treatment of Superficial Pressure Sores. Journal of the American Geriatrics Society 1983; 31:131-133.

Zmudzka BZ & Beer JZ. Ultraviolet therapy and patients with HIV infection. Arch Dermatol. 1998; 134; 1025-1026.

PNEUMATIC COMPRESSION PUMPS

Coleridge et al. 1990. Sequential gradient pneumatic compression enhances venous ulcer healing. A RCT. Surgery 108: 871-5.

Gaylarde et al. 1993. The effect of compression on venous stasis. Br. J. Dermatol 128: 255-8.

Griffin JW et al. 1990. Reduction of Chronic Posttraumatic Hand Edema: A Comparison of HVPC, IPC, and Placebo Treatments. Phys Ther 70:279-286.

Kolari PI, Pekanmaki K, 1986. Intermittent pneumatic compression in healing of venous ulcers. Lancet 2:1108.

McCulloch J, 1991. Intermittent compression in the treatment of a chronic stasis ulceration. Phys Ther 61(10):1452-5.

Mulder G et al., 1990. Study of sequential compression therapy in the treatment of nonhealing chronic venous ulcers. Wounds 2:111-5.

Richmond DM et al., 1985. Sequential pneumatic compression for lymphedema. Arch. Surg. 20:1116-9.

VACUUM ASSISTED CLOSURE

Argenta LC, Morykwas MJ. Vacuum assisted closure: A new method for wound control an treatment: Clinical experience. Ann Plast Surg 38, 563, 1997.

Philbeck TE, Whittington KT, Millsap MH, Briones RB. Wight DG, Schroeder WJ. The clinical and cost effectiveness of externally applied negative pressure wound therapy in the treatment of wounds in home health care Medicare patients. Ostomy/Wound Mangement 1999 45(11):41-50.

McCallon S, Knight A, Valiulis J, Cunningham M, McCulloch J, Farinas L. Effectiveness of vacuum assisted closure vs saline moistened gauze in the healing of post-operative diabetic foot wounds. A pilot study. Ostomy/Wound Manage 2000 (in press).

Mullner T et al. The use of negative pressure to promote the healing of tissue defects: A clinical trial usuing the vacuum seal technique. Br J Plast Surg 50;194, 1997.

HYDROTHERAPY: Whirlpool & Pulsed Lavage

Bohannon RW. Whirlpool versus whirlpool rinse for removal of decubitus ulcers. Nurs Res 1984;33:303-305.

Luedtke-Hoffman KA, Schafer DS. Pulsed lavage in wound cleansing. Phys Ther 2000;80(3):292-300.

McCulloch JM, Boyd VB. The effects of whirlpool and the dependent position on lower extremity volume. JOSPT 1992;169-173.

Niederhuber S, Stribley RF, Koepke GH. Reduction of skin bacterial load with use of therapeutic whirlpool. Phys Ther 1975;55(5):482-6.

Solomon SL. Host factors in whirlpool-associated pseudomonas Aeruginosa skin disease. Infect Control. 1985;6:402-406.

NORMOTHERMIA

Cherry, GW and Wilson J. The treatment of ambulatory venous ulcer patients with warming therapy. Ostomy Wound Manage 45;65, 1999

Kloth LC et al. Effects of heated and unheated Warm Up dressings on full thickness pressure ulcers. Adv Skin Wound Care 13;69, 2000.

Price P et al. The effect of a radiant heat dressings on pressure ulcers. J Wound Care 9;203, 2000.

Santilli SM et al. Use of non contact radiant heat bandage for the treatment of chronic venous stasis ulcers. Adv Skin Wound Care 12:89, 1999.

GROWTH FACTORS

Robson MC, Phillips LG, Thomason A, Robson LE, Pierce GF. Platelet derived growth factor —BB in the treatment of chronic pressure ulcers. Lancet 339;23-25, 1992.

Mustoe TA, Cutler NR, Allman RM, et al., A phase II study to evaluate recombinant PDGF-BB in the treatment of stage 3 and 4 pressure ulcers. Arch Surg 129(2);213-219, 1994.

Rees RS, Robson MC, Smiell JM, Perry BH. Becalpermin gel in the treatment of pressure ulcers: A phase II randomized, double blind, placebo-controlled study. Wound Repair Regen; 7(3); 141-147, 1999.

Steed DL. Clinical evaluation of recombinant human platelet derived growth factor for the treatment of lower extremity diabetic ulcers. Diabetic ulcer study group. J Vasc Surg 2(1); 71-81, 1995.

Smiell JM, Wierman TJ, Steed DL, Perry DH, Sampson AR, Schwab BH. Efficacy and safety of becalpermin (recombinant human platelet derived growth factor BB) in patients with non healing, lower extremity diabetic ulcers: A combined analysis of four randomized studies. Wound Repair Regen 7(5); 335-346, 1999.

Robson MC, Phillips LG, Cooper DM et al. The safety and effect of transforming growth factor Beta 2 for thet treatment of venous stasis ulcers. Wound Repair Regen 3; 157-167, 1995.

Richard JL, Parer-Richard C, Daures JP, et al. Effect of topical basic fibroblast growth factor on the healing of chronic diabetic neuropathic ulcer of the foot. A pilot, randomized, double blind, placebo-controlled study. Diabetes Care 18; 64-69, 1995.

Robson MC, Phillips LG, Lawrence WT et al. The safety and effect of topically applied recombinant basic fibroblast growth factor on healing of chronic pressure sores. Am Surg 216; 401-408, 1992.

Falanga V, Eaglestein WH, Bucalo B, Katz MH, Harris B, Carson P. Topical use of human recombinant epidermal growth factor (h-EGF) in venous ulcers. J Dermatol Surg Oncol 18; 604-606, 1992.

Jasche E, Zabernigg A, Gattringer C. Recombinant human granulocyte-macrophage colony stimulating factor applied locally in low doses enhances healing and prevents recurrence of chronic venous ulcers. Int J Dermatol 38(3); 350-356, 1999.

Marques Da Costa R, Jesus FM, Aniceto C, Mendes M. Double blind randomized placebo-controlled trial of the use of human granulocyte-macrophage colony stimulating factor in chronic leg ulcers. Am J Surg 173f(3); 165-168, 1997.

Robson LE, Scheeler S. Safety and effect of topical recombinant human interleukin-1B in the management of pressure sores. Wound Repair Regen 2; 177-181, 1994.

SKIN SUBSTITUTES

Polak RA, Edington H, Jensen JL, et al. A human dermal replacement for the treatment of diabetic foot ulcers. WOUNDS 9; 175-183, 1997

Gentzkow GD, Jensen JL, Pollak RA, et al. Improved healing of diabetic foot ulcers after grafting with a living human dermal replacement. WOUNDS 11; 77-84, 1999.

Pham HT, Rosenblum BI, Lyons TE, et al. Evaluation of a human skin equivalent for the treatment of diabetic foot ulcers in a prospective, randomized, clinical trial. WOUNDS 11; 79-86, 1999.

Brem H, Balledux J, Bloom TBA, et al. Healing of diabetic foot ulcers and pressure ulcers with human skin equivalent: a new paradigm in wound healing. Arch Surg 135; 627-634, 2000.

Sibbald RG, Torrance G, MacNeil P, et al. A cost effectiveness analysis of high compression therapy with and without Apligraf in the treatment of venous leg ulcers. Ostomy Wound Manage; 47(2); 46, 2001.

Back to Research
     
   

Please contact us at: cawc@sympatico.ca.

© CAWC 2003
Last modified:
March 20, 2003